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» The Logical Structure of Binding
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BMCBI
2008
108views more  BMCBI 2008»
15 years 6 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher
CORR
2010
Springer
105views Education» more  CORR 2010»
15 years 6 months ago
Molecular Recognition as an Information Channel: The Role of Conformational Changes
Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a ...
Yonatan Savir, Tsvi Tlusty
156
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BMCBI
2006
98views more  BMCBI 2006»
15 years 6 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
DA
2007
69views more  DA 2007»
15 years 6 months ago
e-Participation and Decision Analysis
Decision analytic methods are now used frequently to help articulate and structure debate and deliberations among citizens and stakeholders in societal decisions. Methods vary, bu...
Simon French, David Ríos Insua, Fabrizio Ru...
ENTCS
2007
100views more  ENTCS 2007»
15 years 6 months ago
Type-Safe Code Transformations in Haskell
The use of typed intermediate languages can significantly increase the reliability of a compiler. By typechecking the code produced at each transformation stage, one can identify...
Louis-Julien Guillemette, Stefan Monnier