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» The Logical Structure of Binding
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BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2007
77views more  BMCBI 2007»
15 years 6 months ago
The reactive metabolite target protein database (TPDB) - a web-accessible resource
Background: The toxic effects of many simple organic compounds stem from their biotransformation to chemically reactive metabolites which bind covalently to cellular proteins. To ...
Robert P. Hanzlik, Yakov M. Koen, Bhargav Theertha...
JCB
2006
138views more  JCB 2006»
15 years 6 months ago
Recognition and Classification of Histones Using Support Vector Machine
Histones are DNA-binding proteins found in the chromatin of all eukaryotic cells. They are highly conserved and can be grouped into five major classes: H1/H5, H2A, H2B, H3, and H4...
Manoj Bhasin, Ellis L. Reinherz, Pedro A. Reche
BMCBI
2005
148views more  BMCBI 2005»
15 years 6 months ago
NemaFootPrinter: a web based software for the identification of conserved non-coding genome sequence regions between C. elegans
Background: NemaFootPrinter (Nematode Transcription Factor Scan Through Philogenetic Footprinting) is a web-based software for interactive identification of conserved, non-exonic ...
Davide Rambaldi, Alessandro Guffanti, Paolo Morand...
NAR
2002
89views more  NAR 2002»
15 years 6 months ago
Transcription Regulatory Regions Database (TRRD): its status in 2002
Transcription Regulatory Regions Database (TRRD) is an informational resource containing an integrated description of the gene transcription regulation. An entry of the database c...
Nikolay A. Kolchanov, Elena V. Ignatieva, Elena A....