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» The LIFEdb database in 2006
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BMCBI
2006
180views more  BMCBI 2006»
15 years 6 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2006
160views more  BMCBI 2006»
15 years 6 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2006
107views more  BMCBI 2006»
15 years 6 months ago
CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
Jussi Paananen, Markus Storvik, Garry Wong
BMCBI
2006
89views more  BMCBI 2006»
15 years 6 months ago
ORENZA: a web resource for studying ORphan ENZyme activities
Background: Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclat...
Olivier Lespinet, Bernard Labedan
BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...