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BMCBI
2007
207views more  BMCBI 2007»
15 years 6 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2006
126views more  BMCBI 2006»
15 years 6 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
APIN
2004
116views more  APIN 2004»
15 years 6 months ago
Neural Learning from Unbalanced Data
This paper describes the result of our study on neural learning to solve the classification problems in which data is unbalanced and noisy. We conducted the study on three differen...
Yi Lu Murphey, Hong Guo, Lee A. Feldkamp
BMCBI
2004
153views more  BMCBI 2004»
15 years 6 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2010
140views more  BMCBI 2010»
15 years 4 months ago
An improved machine learning protocol for the identification of correct Sequest search results
Background: Mass spectrometry has become a standard method by which the proteomic profile of cell or tissue samples is characterized. To fully take advantage of tandem mass spectr...
Morten Kallberg, Hui Lu