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181
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BMCBI
2004
15 years 6 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
213
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BMCBI
2004
15 years 6 months ago
2004
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
223
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BMCBI
2004
15 years 6 months ago
2004
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...
199
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BMCBI
2004
15 years 6 months ago
2004
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
192
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BMCBI
2004
15 years 6 months ago
2004
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...