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181
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BMCBI
2004
15 years 6 months ago
2004
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
198
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BMCBI
2004
15 years 6 months ago
2004
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
191
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BMCBI
2004
15 years 6 months ago
2004
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
184
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BMCBI
2004
15 years 6 months ago
2004
Background: Because loops connect regular secondary structures, analysis of the former depends directly on the definition of the latter. The numerous assignment methods, however, ...
167
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BMCBI
2004
15 years 6 months ago
2004
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...