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BMCBI
2005
89views more  BMCBI 2005»
15 years 6 months ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
BMCBI
2005
104views more  BMCBI 2005»
15 years 6 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2005
98views more  BMCBI 2005»
15 years 6 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
BMCBI
2005
82views more  BMCBI 2005»
15 years 6 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
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