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BMCBI
2011
15 years 1 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
ICDE
2008
IEEE
129views Database» more  ICDE 2008»
16 years 8 months ago
Optimal Boolean Matrix Decomposition: Application to Role Engineering
Abstract-- A decomposition of a binary matrix into two matrices gives a set of basis vectors and their appropriate combination to form the original matrix. Such decomposition solut...
Haibing Lu, Jaideep Vaidya, Vijayalakshmi Atluri
KDD
2007
ACM
177views Data Mining» more  KDD 2007»
16 years 7 months ago
Mining optimal decision trees from itemset lattices
We present DL8, an exact algorithm for finding a decision tree that optimizes a ranking function under size, depth, accuracy and leaf constraints. Because the discovery of optimal...
Élisa Fromont, Siegfried Nijssen
RECOMB
2008
Springer
16 years 7 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
VLDB
2008
ACM
103views Database» more  VLDB 2008»
16 years 7 months ago
The optimal sequenced route query
Several variations of nearest neighbor (NN) query have been investigated by the database community. However, realworld applications often result in the formulation of new variatio...
Mehdi Sharifzadeh, Mohammad R. Kolahdouzan, Cyrus ...