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BMCBI
2010
141views more  BMCBI 2010»
15 years 6 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
BMCBI
2010
167views more  BMCBI 2010»
15 years 6 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
ALGORITHMICA
2006
139views more  ALGORITHMICA 2006»
15 years 6 months ago
CONQUEST: A Coarse-Grained Algorithm for Constructing Summaries of Distributed Discrete Datasets
Abstract. In this paper we present a coarse-grained parallel algorithm, CONQUEST, for constructing boundederror summaries of high-dimensional binary attributed data in a distribute...
Jie Chi, Mehmet Koyutürk, Ananth Grama
BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
15 years 6 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...