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EUROPAR
2010
Springer
15 years 7 months ago
Multithreaded Geant4: Semi-automatic Transformation into Scalable Thread-Parallel Software
This work presents an application case study. Geant4 is a 750,000 line toolkit first designed in the mid-1990s and originally intended only for sequential computation. Intel's...
Xin Dong 0004, Gene Cooperman, John Apostolakis
BMCBI
2008
57views more  BMCBI 2008»
15 years 6 months ago
A novel method for high accuracy sumoylation site prediction from protein sequences
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
Jialin Xu, Yun He, Boqin Qiang, Jiangang Yuan, Xia...
BMCBI
2006
97views more  BMCBI 2006»
15 years 6 months ago
PDA: Pooled DNA analyzer
Background: Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring pos...
Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy...
CORR
2007
Springer
128views Education» more  CORR 2007»
15 years 6 months ago
Model Selection Through Sparse Maximum Likelihood Estimation
We consider the problem of estimating the parameters of a Gaussian or binary distribution in such a way that the resulting undirected graphical model is sparse. Our approach is to...
Onureena Banerjee, Laurent El Ghaoui, Alexandre d'...
BMCBI
2004
81views more  BMCBI 2004»
15 years 6 months ago
Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis
Background: Mutations in rpoB, the gene encoding the subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studi...
Michael P. Cummings, Mark R. Segal