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BMCBI
2007
121views more  BMCBI 2007»
15 years 6 months ago
A constrained polynomial regression procedure for estimating the local False Discovery Rate
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...
Cyril Dalmasso, Avner Bar-Hen, Philippe Broët
BMCBI
2008
62views more  BMCBI 2008»
15 years 6 months ago
Filtering of false positive microRNA candidates by a clustering-based approach
Background: MicroRNAs are small non-coding RNA gene products that play diversified roles from species to species. The explosive growth of microRNA researches in recent years prove...
Wing-Sze Leung, Marie C. M. Lin, David Wai-Lok Che...
BMCBI
2010
144views more  BMCBI 2010»
15 years 6 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2010
155views more  BMCBI 2010»
15 years 6 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
BMCBI
2008
141views more  BMCBI 2008»
15 years 6 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...