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» Tests for gene clustering
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BMCBI
2008
122views more  BMCBI 2008»
15 years 6 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
BMCBI
2008
200views more  BMCBI 2008»
15 years 6 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2007
227views more  BMCBI 2007»
15 years 6 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
CATA
2009
15 years 7 months ago
Nearest Shrunken Centroid as Feature Selection of Microarray Data
The nearest shrunken centroid classifier uses shrunken centroids as prototypes for each class and test samples are classified to belong to the class whose shrunken centroid is nea...
Myungsook Klassen, Nyunsu Kim
BMCBI
2004
79views more  BMCBI 2004»
15 years 6 months ago
A new mixture model approach to analyzing allelic-loss data using Bayes factors
Background: Allelic-loss studies record data on the loss of genetic material in tumor tissue relative to normal tissue at various loci along the genome. As the deletion of a tumor...
Manisha Desai, Mary J. Emond