Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
The nearest shrunken centroid classifier uses shrunken centroids as prototypes for each class and test samples are classified to belong to the class whose shrunken centroid is nea...
Background: Allelic-loss studies record data on the loss of genetic material in tumor tissue relative to normal tissue at various loci along the genome. As the deletion of a tumor...