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BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2007
141views more  BMCBI 2007»
15 years 6 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
KAIS
2006
110views more  KAIS 2006»
15 years 6 months ago
Multi-step density-based clustering
Abstract. Data mining in large databases of complex objects from scientific, engineering or multimedia applications is getting more and more important. In many areas, complex dista...
Stefan Brecheisen, Hans-Peter Kriegel, Martin Pfei...
TASE
2008
IEEE
15 years 6 months ago
New Solution Approaches to the General Single- Machine Earliness-Tardiness Problem
This paper addresses the general single-machine earliness-tardiness problem with distinct release dates, due dates, and unit costs. The aim of this research is to obtain an exact n...
Hoksung Yau, Yunpeng Pan, Leyuan Shi
BMCBI
2005
306views more  BMCBI 2005»
15 years 6 months ago
A method for aligning RNA secondary structures and its application to RNA motif detection
Background: Alignment of RNA secondary structures is important in studying functional RNA motifs. In recent years, much progress has been made in RNA motif finding and structure a...
Jianghui Liu, Jason Tsong-Li Wang, Jun Hu, Bin Tia...