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BMCBI
2008
117views more  BMCBI 2008»
15 years 6 months ago
An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass sp
Background: Metabolomics, petroleum and biodiesel chemistry, biomarker discovery, and other fields which rely on high-resolution profiling of complex chemical mixtures generate da...
Minho Chae, Robert J. Shmookler Reis, John J. Thad...
BMCBI
2006
148views more  BMCBI 2006»
15 years 6 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
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BMCBI
2006
174views more  BMCBI 2006»
15 years 6 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
IJON
2007
74views more  IJON 2007»
15 years 6 months ago
Visual object concept discovery: Observations in congenitally blind children, and a computational approach
Over the course of the first few months of life, our brains accomplish a remarkable feat. They are able to interpret complex visual images so that instead of being just disconnec...
Jake V. Bouvrie, Pawan Sinha
BMCBI
2005
106views more  BMCBI 2005»
15 years 6 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...