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ISMB
1998
15 years 8 months ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
CVPR
2008
IEEE
15 years 7 months ago
Meshless deformable models for LV motion analysis
We propose a novel meshless deformable model for in vivo cardiac left ventricle (LV) 3D motion estimation. As a relatively new technology, tagged MRI (tMRI) provides a direct and ...
Xiaoxu Wang, Dimitris N. Metaxas, Ting Chen, Leon ...
BMCBI
2007
114views more  BMCBI 2007»
15 years 7 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
BMCBI
2008
159views more  BMCBI 2008»
15 years 7 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
BMCBI
2007
141views more  BMCBI 2007»
15 years 7 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...