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GECCO
2006
Springer
172views Optimization» more  GECCO 2006»
15 years 10 months ago
Multi-objective optimisation of the protein-ligand docking problem in drug discovery
The pharmaceutical industry is facing an ever-increasing demand to discover novel drugs that are more effective and safer than existing ones. The industry faces huge problem in im...
A. Oduguwa, A. Tiwari, S. Fiorentino, R. Roy
CVPR
2000
IEEE
15 years 10 months ago
Adaptive Metric nearest Neighbor Classification
Nearest neighbor classification assumes locally constant class conditional probabilities. This assumption becomes invalid in high dimensions with finite samples due to the curse o...
Carlotta Domeniconi, Dimitrios Gunopulos, Jing Pen...
IWAN
2000
Springer
15 years 10 months ago
Active Networking Means Evolution (or Enhanced Extensibility Required)
The primary goal of active networking is to increase the pace of network evolution. The approach to achieving this goal, as well as the goal of enhancing customizability, is to al...
Michael W. Hicks, Scott Nettles
ASPLOS
1991
ACM
15 years 10 months ago
The Cache Performance and Optimizations of Blocked Algorithms
Blocking is a well-known optimization technique for improving the effectiveness of memory hierarchies. Instead of operating on entire rows or columns of an array, blocked algorith...
Monica S. Lam, Edward E. Rothberg, Michael E. Wolf
QOSA
2010
Springer
15 years 9 months ago
Parameterized Reliability Prediction for Component-Based Software Architectures
Critical properties of software systems, such as reliability, should be considered early in the development, when they can govern crucial architectural design decisions. A number o...
Franz Brosch, Heiko Koziolek, Barbora Buhnova, Ral...