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BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
BMCBI
2008
102views more  BMCBI 2008»
15 years 6 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes
CORR
2010
Springer
152views Education» more  CORR 2010»
15 years 6 months ago
Neuroevolutionary optimization
Temporal difference methods are theoretically grounded and empirically effective methods for addressing reinforcement learning problems. In most real-world reinforcement learning ...
Eva Volná
BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
Recrafting the neighbor-joining method
Background: The neighbor-joining method by Saitou and Nei is a widely used method for constructing phylogenetic trees. The formulation of the method gives rise to a canonical (n3)...
Thomas Mailund, Gerth Stølting Brodal, Rolf...
ISI
2008
Springer
15 years 6 months ago
Probabilistic frameworks for privacy-aware data mining
Often several cooperating parties would like to have a global view of their joint data for various data mining objectives, but cannot reveal the contents of individual records due...
Joydeep Ghosh