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BMCBI
2010
97views more  BMCBI 2010»
15 years 6 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
BMCBI
2008
141views more  BMCBI 2008»
15 years 6 months ago
Functional discrimination of membrane proteins using machine learning techniques
Background: Discriminating membrane proteins based on their functions is an important task in genome annotation. In this work, we have analyzed the characteristic features of amin...
M. Michael Gromiha, Yukimitsu Yabuki
BMCBI
2010
243views more  BMCBI 2010»
15 years 6 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
ICIP
2009
IEEE
16 years 7 months ago
Skewed Log-stable Model For Natural Images Pixel Block-variance
This work presents a Log-stable model for natural images blockvariance. Exponential and halfnormal distributions have been previously used to model block-variance, but they were e...
ICSE
2008
IEEE-ACM
16 years 7 months ago
On the difficulty of replicating human subjects studies in software engineering
Replications play an important role in verifying empirical results. In this paper, we discuss our experiences performing a literal replication of a human subjects experiment that ...
Jonathan Lung, Jorge Aranda, Steve M. Easterbrook,...