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BMCBI
2005
93views more  BMCBI 2005»
15 years 5 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2005
82views more  BMCBI 2005»
15 years 5 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
BMCBI
2005
106views more  BMCBI 2005»
15 years 5 months ago
Thesaurus-based disambiguation of gene symbols
Background: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene s...
Bob J. A. Schijvenaars, Barend Mons, Marc Weeber, ...
BMCBI
2005
98views more  BMCBI 2005»
15 years 5 months ago
InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data
Background: Good statistical models for analyzing and simulating multilocus recombination data exist but are not accessible to many biologists because their use requires reasonabl...
Lalitha Viswanath, Elizabeth A. Housworth
BMCBI
2005
128views more  BMCBI 2005»
15 years 5 months ago
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process
Background: Biological Mass Spectrometry is used to analyse peptides and proteins. A mass spectrum generates a list of measured mass to charge ratios and intensities of ionised pe...
Witold E. Wolski, Maciej Lalowski, Peter Martus, R...
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