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BMCBI
2010
130views more  BMCBI 2010»
15 years 6 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
89views more  BMCBI 2010»
15 years 6 months ago
Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in gene
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
Antonio Deiana, Andrea Giansanti
BMCBI
2010
137views more  BMCBI 2010»
15 years 6 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2010
111views more  BMCBI 2010»
15 years 6 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2010
153views more  BMCBI 2010»
15 years 6 months ago
PPLook: an automated data mining tool for protein-protein interaction
Background: Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of inter...
Shao-Wu Zhang, Yao-Jun Li, Li Xia, Quan Pan
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