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BMCBI
2006
85views more  BMCBI 2006»
15 years 6 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
JMLR
2002
89views more  JMLR 2002»
15 years 6 months ago
A Robust Minimax Approach to Classification
When constructing a classifier, the probability of correct classification of future data points should be maximized. We consider a binary classification problem where the mean and...
Gert R. G. Lanckriet, Laurent El Ghaoui, Chiranjib...
BMCBI
2011
14 years 10 months ago
Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure
Background: Protein secondary structure prediction provides insight into protein function and is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic ...
Zafer Aydin, Ajit Singh, Jeff Bilmes, William Staf...
FUIN
2011
358views Cryptology» more  FUIN 2011»
14 years 10 months ago
Unsupervised and Supervised Learning Approaches Together for Microarray Analysis
In this article, a novel concept is introduced by using both unsupervised and supervised learning. For unsupervised learning, the problem of fuzzy clustering in microarray data as ...
Indrajit Saha, Ujjwal Maulik, Sanghamitra Bandyopa...
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JCIT
2010
127views more  JCIT 2010»
15 years 1 months ago
Review of PSE (Problem Solving Environment) Study
This review paper presents an overview of the current state of the art in Problem Solving Environments (PSE). PSE provides integrated human-friendly innovative computational servi...
Shigeo Kawata