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BMCBI
2007
207views more  BMCBI 2007»
15 years 7 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2008
167views more  BMCBI 2008»
15 years 7 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli
BMCBI
2008
105views more  BMCBI 2008»
15 years 7 months ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
CORR
2007
Springer
105views Education» more  CORR 2007»
15 years 6 months ago
Relative-Error CUR Matrix Decompositions
Many data analysis applications deal with large matrices and involve approximating the matrix using a small number of “components.” Typically, these components are linear combi...
Petros Drineas, Michael W. Mahoney, S. Muthukrishn...
BMCBI
2005
124views more  BMCBI 2005»
15 years 6 months ago
Internet-based profiler system as integrative framework to support translational research
Background: Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to dev...
Robert Kim, Francesca Demichelis, Jeffery Tang, Al...