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BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
NAR
2008
116views more  NAR 2008»
15 years 6 months ago
SuperPred: drug classification and target prediction
The drug classification scheme of the World Health Organization (WHO) [Anatomical Therapeutic Chemical (ATC)-code] connects chemical classification and therapeutic approach. It is...
Mathias Dunkel, Stefan Günther, Jessica Ahmed...
BMCBI
2011
14 years 10 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
CPM
2005
Springer
97views Combinatorics» more  CPM 2005»
15 years 12 months ago
On the Complexity of Sparse Exon Assembly
Gene structure prediction is one of the most important problems in computational molecular biology. It involves two steps: the first is finding the evidence (e.g. predicting spl...
Carmel Kent, Gad M. Landau, Michal Ziv-Ukelson
ICDM
2009
IEEE
202views Data Mining» more  ICDM 2009»
15 years 4 months ago
Link Prediction on Evolving Data Using Matrix and Tensor Factorizations
Abstract--The data in many disciplines such as social networks, web analysis, etc. is link-based, and the link structure can be exploited for many different data mining tasks. In t...
Evrim Acar, Daniel M. Dunlavy, Tamara G. Kolda