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BMCBI
2008
323views more  BMCBI 2008»
15 years 6 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
BMCBI
2008
170views more  BMCBI 2008»
15 years 6 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2008
176views more  BMCBI 2008»
15 years 6 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational scr
Background: Entry of HIV-1 into human lymphoid requires activities of viral envelope glycoproteins gp120 and gp41, and two host-cell proteins, the primary receptor CD4 and a chemo...
Uthaman Gowthaman, Mannu Jayakanthan, Durai Sundar
CONSTRAINTS
2010
126views more  CONSTRAINTS 2010»
15 years 6 months ago
Lexicographically-ordered constraint satisfaction problems
Abstract. We describe a simple CSP formalism for handling multi-attribute preference problems with hard constraints, one that combines hard constraints and preferences so the two a...
Eugene C. Freuder, Robert Heffernan, Richard J. Wa...
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