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BMCBI
2010
129views more  BMCBI 2010»
15 years 6 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2007
168views more  BMCBI 2007»
15 years 6 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin
BMCBI
2008
166views more  BMCBI 2008»
15 years 6 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
MABS
1998
Springer
15 years 10 months ago
Towards Modeling Other Agents: A Simulation-Based Study
In this paper, we present some of our ongoing experimental research towards investigating advantages of modeling other agents in multiagent environments. We attempt to quantify the...
Leonardo Garrido-Luna, Ramón F. Brena, Kati...
CIKM
1997
Springer
15 years 10 months ago
A Framework for the Management of Past Experiences with Time-Extended Situations
: In the context of knowledge management, we focus on the representation and the retrieval of past experiences called cases within the Case-Based Reasoning (CBR) paradigm. CBR is a...
Michel Jaczynski