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BMCBI
2008
226views more  BMCBI 2008»
15 years 6 months ago
ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining
Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
Tianxiao Huan, Andrey Y. Sivachenko, Scott H. Harr...
BMCBI
2008
184views more  BMCBI 2008»
15 years 6 months ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
BMCBI
2008
158views more  BMCBI 2008»
15 years 6 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2008
141views more  BMCBI 2008»
15 years 6 months ago
Ontology-guided data preparation for discovering genotype-phenotype relationships
Complexity of post-genomic data and multiplicity of mining strategies are two limits to Knowledge Discovery in Databases (KDD) in life sciences. Because they provide a semantic fr...
Adrien Coulet, Malika Smaïl-Tabbone, Pascale ...
BMCBI
2008
90views more  BMCBI 2008»
15 years 6 months ago
Ortholog-based protein-protein interaction prediction and its application to inter-species interactions
Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Sheng-An Lee, Chen-hsiung Chan, Chi-Hung Tsai, Jin...
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