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BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2010
208views more  BMCBI 2010»
15 years 6 months ago
Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...
Kasper Stovgaard, Christian Andreetta, Jesper Ferk...
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BMCBI
2008
120views more  BMCBI 2008»
15 years 6 months ago
E-CAI: a novel server to estimate an expected value of Codon Adaptation Index (eCAI)
Background: The Codon Adaptation Index (CAI) is a measure of the synonymous codon usage bias for a DNA or RNA sequence. It quantifies the similarity between the synonymous codon u...
Pere Puigbò, Ignacio G. Bravo, Santiago Gar...
BMCBI
2006
150views more  BMCBI 2006»
15 years 6 months ago
Instance-based concept learning from multiclass DNA microarray data
Background: Various statistical and machine learning methods have been successfully applied to the classification of DNA microarray data. Simple instance-based classifiers such as...
Daniel P. Berrar, Ian Bradbury, Werner Dubitzky