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ISMB
2000
15 years 8 months ago
Mining for Putative Regulatory Elements in the Yeast Genome Using Gene Expression Data
We have developed a set of methods and tools for automatic discovery of putative regulatory signals in genome sequences. The analysis pipeline consists of gene expression data clu...
Jaak Vilo, Alvis Brazma, Inge Jonassen, Alan J. Ro...
ISMB
1993
15 years 8 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
BMCBI
2010
86views more  BMCBI 2010»
15 years 7 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2006
142views more  BMCBI 2006»
15 years 6 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
JColorGrid: software for the visualization of biological measurements
Background: Two-dimensional data colourings are an effective medium by which to represent three-dimensional data in two dimensions. Such "color-grid" representations hav...
Marcin P. Joachimiak, Jennifer L. Weissman, Barnab...