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189
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BMCBI
2006
85views more  BMCBI 2006»
15 years 7 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
161
Voted
BMCBI
2006
120views more  BMCBI 2006»
15 years 7 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BMCBI
2006
136views more  BMCBI 2006»
15 years 7 months ago
Metric for Measuring the Effectiveness of Clustering of DNA Microarray Expression
Background: The recent advancement of microarray technology with lower noise and better affordability makes it possible to determine expression of several thousand genes simultane...
Raja Loganantharaj, Satish Cheepala, John Clifford
267
Voted
BMCBI
2006
202views more  BMCBI 2006»
15 years 7 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
208
Voted
BMCBI
2006
150views more  BMCBI 2006»
15 years 7 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils
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