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BMCBI
2010
104views more  BMCBI 2010»
15 years 7 months ago
A method for automatically extracting infectious disease-related primers and probes from the literature
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
Miguel García-Remesal, Alejandro Cuevas, Vi...
BMCBI
2008
96views more  BMCBI 2008»
15 years 7 months ago
Novel methodology for construction and pruning of quasi-median networks
Background: Visualising the evolutionary history of a set of sequences is a challenge for molecular phylogenetics. One approach is to use undirected graphs, such as median network...
Sarah C. Ayling, Terence A. Brown
BMCBI
2008
116views more  BMCBI 2008»
15 years 7 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
BMCBI
2007
88views more  BMCBI 2007»
15 years 7 months ago
Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
John P. Rasmussen, Christopher P. Saint, Paul T. M...
BMCBI
2007
160views more  BMCBI 2007»
15 years 7 months ago
Optimization based automated curation of metabolic reconstructions
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
Vinay Satish Kumar, Madhukar S. Dasika, Costas D. ...
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