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BMCBI
2010
86views more  BMCBI 2010»
15 years 7 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...
BMCBI
2010
72views more  BMCBI 2010»
15 years 7 months ago
Phylogenetic representativeness: a new method for evaluating taxon sampling in evolutionary studies
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
BMCBI
2010
89views more  BMCBI 2010»
15 years 7 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2010
144views more  BMCBI 2010»
15 years 7 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...
BIOSYSTEMS
2007
107views more  BIOSYSTEMS 2007»
15 years 7 months ago
Calcium signalling in astrocytes and modulation of neural activity
Up to few years ago astrocytes have been considered as passive elements of brain, providing structural and metabolic support to the neurons, but playing little role in information...
Angelo Di Garbo, Michele Barbi, Santi Chillemi, Su...
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