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BMCBI
2010
102views more  BMCBI 2010»
15 years 7 months ago
Identification of recurrent regions of copy-number variants across multiple individuals
Background: Algorithms and software for CNV detection have been developed, but they detect the CNV regions sample-by-sample with individual-specific breakpoints, while common CNV ...
Teo Shu Mei, Agus Salim, Stefano Calza, Ku Chee Se...
BMCBI
2010
136views more  BMCBI 2010»
15 years 7 months ago
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Ma...
BMCBI
2010
109views more  BMCBI 2010»
15 years 7 months ago
Free energy estimation of short DNA duplex hybridizations
Background: Estimation of DNA duplex hybridization free energy is widely used for predicting cross-hybridizations in DNA computing and microarray experiments. A number of software...
Dan C. Tulpan, Mirela Andronescu, Serge Leger
BMCBI
2010
125views more  BMCBI 2010»
15 years 7 months ago
Visualisation tool for peptide fractionation data in proteomics: application to OFFGEL isoelectric focussing
Background: OFFGEL isoelectric focussing (IEF) has become a popular tool in proteomics to fractionate peptides or proteins. As a consequence there is a need for software solutions...
David-Olivier D. Azulay, Hendrik Neubert, Mireia F...
BMCBI
2010
190views more  BMCBI 2010»
15 years 7 months ago
Sample size and statistical power considerations in high-dimensionality data settings: a comparative study of classification alg
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
Yu Guo, Armin Graber, Robert N. McBurney, Raji Bal...
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