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» Software, regulation, and domain specificity
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BMCBI
2010
87views more  BMCBI 2010»
15 years 6 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
IMSCCS
2007
IEEE
16 years 14 days ago
Evolutionary Conservation of DNA-Contact residues in DNA-binding Domains
Background: DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DN...
Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yun...
ICECCS
2000
IEEE
126views Hardware» more  ICECCS 2000»
15 years 10 months ago
Domain Modeling of Software Process Models
This paper presents a novel application involving two important Software Engineering research areas: process modeling and software reuse. The Spiral Model is a risk-driven process...
Hassan Gomaa, Larry Kerschberg, Ghulam A. Farrukh
ARGMAS
2004
Springer
15 years 10 months ago
Formal Dialectic Specification
Formal dialectic systems have been suggested as a means to model inter-agent communication in multi-agent systems. The formal dialectic systems of Hamblin are practical models for ...
Simon Wells, Chris Reed
BIBE
2007
IEEE
142views Bioinformatics» more  BIBE 2007»
16 years 15 days ago
An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...