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BMCBI
2006
122views more  BMCBI 2006»
15 years 6 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2006
94views more  BMCBI 2006»
15 years 6 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
110views more  BMCBI 2006»
15 years 6 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
BMCBI
2006
141views more  BMCBI 2006»
15 years 6 months ago
The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
Background: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of...
Alexander García Castro, Philippe Rocca-Ser...
COMCOM
2006
103views more  COMCOM 2006»
15 years 6 months ago
Research challenges in QoS routing
Quality of Service Routing is at present an active and remarkable research area, since most emerging network services require specialized Quality of Service (QoS) functionalities ...
Xavier Masip-Bruin, Marcelo Yannuzzi, Jordi Doming...
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