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BMCBI
2010
96views more  BMCBI 2010»
15 years 7 months ago
A statistical framework for differential network analysis from microarray data
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Ryan Gill, Somnath Datta, Susmita Datta
BMCBI
2008
97views more  BMCBI 2008»
15 years 7 months ago
A Population Proportion approach for ranking differentially expressed genes
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Mugdha Gadgil
BMCBI
2007
219views more  BMCBI 2007»
15 years 7 months ago
MetaQTL: a package of new computational methods for the meta-analysis of QTL mapping experiments
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
Jean-Baptiste Veyrieras, Bruno Goffinet, Alain Cha...
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BMCBI
2007
94views more  BMCBI 2007»
15 years 7 months ago
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
ISCA
2006
IEEE
145views Hardware» more  ISCA 2006»
15 years 6 months ago
Techniques for Multicore Thermal Management: Classification and New Exploration
Power density continues to increase exponentially with each new technology generation, posing a major challenge for thermal management in modern processors. Much past work has exa...
James Donald, Margaret Martonosi