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BMCBI
2005
81views more  BMCBI 2005»
15 years 6 months ago
Evolutionary sequence analysis of complete eukaryote genomes
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
Jaime E. Blair, Prachi Shah, S. Blair Hedges
BMCBI
2005
144views more  BMCBI 2005»
15 years 6 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
BMCBI
2004
196views more  BMCBI 2004»
15 years 6 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
PR
2011
15 years 1 months ago
A sum-over-paths extension of edit distances accounting for all sequence alignments
This paper introduces a simple Sum-over-Paths (SoP) formulation of string edit distances accounting for all possible alignments between two sequences, and extends related previous...
Silvia García-Díez, François ...
ECCB
2008
IEEE
16 years 1 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial