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ALMOB
2008
112views more  ALMOB 2008»
15 years 6 months ago
Metabolite-based clustering and visualization of mass spectrometry data using one-dimensional self-organizing maps
Background: One of the goals of global metabolomic analysis is to identify metabolic markers that are hidden within a large background of data originating from high-throughput ana...
Peter Meinicke, Thomas Lingner, Alexander Kaever, ...
BIOINFORMATICS
2010
116views more  BIOINFORMATICS 2010»
15 years 6 months ago
A principal skeleton algorithm for standardizing confocal images of fruit fly nervous systems
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
Lei Qu, Hanchuan Peng
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
15 years 6 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble