Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Many real life problems require the classification of items into naturally ordered classes. These problems are traditionally handled by conventional methods intended for the class...
Background: Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways. Isotope labeling ...
Michael Weitzel, Wolfgang Wiechert, Katharina N&ou...
Using a previously developed automated method for enzyme annotation, we report the reannotation of the ENZYME database and the analysis of local error rates per class. In control ...
Benjamin Audit, Emmanuel D. Levy, Walter R. Gilks,...