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BMCBI
2010
120views more  BMCBI 2010»
15 years 6 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
MAID : An effect size based model for microarray data integration across laboratories and platforms
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
CN
2010
149views more  CN 2010»
15 years 6 months ago
A collaborative P2P scheme for NAT Traversal Server discovery based on topological information
In the current Internet picture more than 70% of the hosts are located behind Network Address Translators (NATs). This is not a problem in the client/server paradigm. However, the...
Rubén Cuevas Rumín, Ángel Cue...
BMCBI
2006
147views more  BMCBI 2006»
15 years 6 months ago
QPath: a method for querying pathways in a protein-protein interaction network
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...
BMCBI
2006
133views more  BMCBI 2006»
15 years 6 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen