1335 search results - page 76 / 267 » Shotgun Protein Sequencing |
175
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BIOCOMP
2009
15 years 7 months ago
2009
Abstract-- Stating protein design as an energy minimization in the space of amino acid sequences and rotamer combinations is usual. In the current paper an evolutionary algorithm b...
129
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BMCBI
2007
15 years 6 months ago
2007
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
201
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BMCBI
2005
15 years 6 months ago
2005
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
187
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BMCBI
2010
15 years 1 months ago
2010
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
179
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BMCBI
2006
15 years 6 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...