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ISMB
1994
15 years 7 months ago
An Efficient Method for Multiple Sequence Alignment
Multiple sequence alignment has been a useful methodin the study of molecular evolution and sequence-structure relationships. This paper presents a newmethodfor multiple sequence ...
Jin Kim, Sakti Pramanik
NIPS
2004
15 years 7 months ago
A Hidden Markov Model for de Novo Peptide Sequencing
De novo Sequencing of peptides is a challenging task in proteome research. While there exist reliable DNA-sequencing methods, the highthroughput de novo sequencing of proteins by ...
Bernd Fischer, Volker Roth, Joachim M. Buhmann, Jo...
BMCBI
2010
86views more  BMCBI 2010»
15 years 6 months ago
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Evgeniy V. Petrotchenko, Christoph H. Borchers
BMCBI
2010
177views more  BMCBI 2010»
15 years 6 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...