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» Shotgun Protein Sequencing
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PSB
2001
15 years 7 months ago
PIES, A Protein Interaction Extraction System
We consider the problem of extracting, manipulating, and managing biological pathways, especially protein-protein interaction pathways. We discuss here the Protein Interaction Ext...
Limsoon Wong
NAR
2000
85views more  NAR 2000»
15 years 6 months ago
MitoNuc and MitoAln: two related databases of nuclear genes coding for mitochondrial proteins
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Graziano Pesole, Carmela Gissi, Domenico Catalano,...
BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...