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BMCBI
2010
117views more  BMCBI 2010»
15 years 6 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
BMCBI
2007
126views more  BMCBI 2007»
15 years 6 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
16 years 26 days ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
CIBCB
2006
IEEE
16 years 14 days ago
Optimization of the Sliding Window Size for Protein Structure Prediction
- Sliding window based methods are relatively often applied in prediction of various aspects related to protein structure. Despite their wide spread use, researchers did not establ...
Ke Chen, Lukasz A. Kurgan, Jishou Ruan
RECOMB
2005
Springer
15 years 12 months ago
Examination of the tRNA Adaptation Index as a Predictor of Protein Expression Levels
Phenotypic differences between closely-related species may arise from differential expression regimes, rather than different gene complements. Knowledge of cellular protein levels ...
Orna Man, Joel L. Sussman, Yitzhak Pilpel