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NAR
2011
188views Computer Vision» more  NAR 2011»
14 years 9 months ago
ThYme: a database for thioester-active enzymes
The ThYme (Thioester-active enzYme; http://www .enzyme.cbirc.iastate.edu) database has been constructed to bring together amino acid sequences and 3D (tertiary) structures of all ...
David C. Cantu, Yingfei Chen, Matthew L. Lemons, P...
BMCBI
2005
152views more  BMCBI 2005»
15 years 6 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
16 years 26 days ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
NAR
2000
122views more  NAR 2000»
15 years 6 months ago
ProDom and ProDom-CG: tools for protein domain analysis and whole genome comparisons
ProDom contains all protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases (http://www.toulouse. inra.fr/prodom.html ). ProDom-CG result...
Florence Corpet, Florence Servant, Jér&ocir...
BMCBI
2011
15 years 1 months ago
DecGPU: distributed error correction on massively parallel graphics processing units using CUDA and MPI
Background: Next-generation sequencing technologies have led to the high-throughput production of sequence data (reads) at low cost. However, these reads are significantly shorter...
Yongchao Liu, Bertil Schmidt, Douglas L. Maskell