Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...
The availability of a direct pathway from a primary sequence (denovo or DNA derived) to macromolecular structure to biological function using computer-based tools is the ultimate ...
Background: As one of the most common protein post-translational modifications, glycosylation is involved in a variety of important biological processes. Computational identificat...
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Background: The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as `states'...