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BMCBI
2010
87views more  BMCBI 2010»
15 years 6 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2006
92views more  BMCBI 2006»
15 years 6 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
WABI
2007
Springer
16 years 15 days ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
TOG
2002
109views more  TOG 2002»
15 years 6 months ago
Level set surface editing operators
We present a level set framework for implementing editing operators for surfaces. Level set models are deformable implicit surfaces where the deformation of the surface is control...
Ken Museth, David E. Breen, Ross T. Whitaker, Alan...
CPM
2000
Springer
160views Combinatorics» more  CPM 2000»
15 years 10 months ago
Approximation Algorithms for Hamming Clustering Problems
We study Hamming versions of two classical clustering problems. The Hamming radius p-clustering problem (HRC) for a set S of k binary strings, each of length n, is to find p bina...
Leszek Gasieniec, Jesper Jansson, Andrzej Lingas