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BMCBI
2008
103views more  BMCBI 2008»
15 years 6 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
BMCBI
2006
96views more  BMCBI 2006»
15 years 6 months ago
Bayesian detection of periodic mRNA time profiles without use of training examples
Background: Detection of periodically expressed genes from microarray data without use of known periodic and non-periodic training examples is an important problem, e.g. for ident...
Claes R. Andersson, Anders Isaksson, Mats G. Gusta...
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
CORR
2006
Springer
118views Education» more  CORR 2006»
15 years 6 months ago
Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge s
The organization and mining of malaria genomic and post-genomic data is important to significantly increase the knowledge of the biology of its causative agents, and is motivated,...
L.-M. Birkholtz, Olivier Bastien, G. Wells, D. Gra...
BMCBI
2007
94views more  BMCBI 2007»
15 years 6 months ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
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