Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Abstract. Ambiguity in dynamic programming arises from two independent sources, the non-uniqueness of optimal solutions and the particular recursion scheme by which the search spac...
Segmentation of deep brain structures is a challenging task for MRI images due to blurry structure boundaries, small object size and irregular shapes. In this paper, we present a ...