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BMCBI
2006
152views more  BMCBI 2006»
15 years 6 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
Predicting the protein-protein interactions using primary structures with predicted protein surface
Background: Many biological functions involve various protein-protein interactions (PPIs). Elucidating such interactions is crucial for understanding general principles of cellula...
Darby Tien-Hao Chang, Yu-Tang Syu, Po-Chang Lin
BMCBI
2010
175views more  BMCBI 2010»
15 years 6 months ago
Towards high performance computing for molecular structure prediction using IBM Cell Broadband Engine - an implementation perspe
Background: RNA structure prediction problem is a computationally complex task, especially with pseudo-knots. The problem is well-studied in existing literature and predominantly ...
S. P. T. Krishnan, Sim Sze Liang, Bharadwaj Veerav...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
PocketMatch: A new algorithm to compare binding sites in protein structures
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
Kalidas Yeturu, Nagasuma Chandra
CSDA
2006
169views more  CSDA 2006»
15 years 6 months ago
Generalized structured additive regression based on Bayesian P-splines
Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Ba...
Andreas Brezger, Stefan Lang