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BMCBI
2007
153views more  BMCBI 2007»
15 years 6 months ago
Lower bounds on multiple sequence alignment using exact 3-way alignment
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...
Charles J. Colbourn, Sudhir Kumar
SIGECOM
2008
ACM
155views ECommerce» more  SIGECOM 2008»
15 years 6 months ago
Tight information-theoretic lower bounds for welfare maximization in combinatorial auctions
We provide tight information-theoretic lower bounds for the welfare maximization problem in combinatorial auctions. In this problem, the goal is to partition m items among k bidde...
Vahab S. Mirrokni, Michael Schapira, Jan Vondr&aac...
QRE
2008
140views more  QRE 2008»
15 years 5 months ago
Discrete mixtures of kernels for Kriging-based optimization
: Kriging-based exploration strategies often rely on a single Ordinary Kriging model which parametric covariance kernel is selected a priori or on the basis of an initial data set....
David Ginsbourger, Céline Helbert, Laurent ...
TC
2010
15 years 4 months ago
Network-on-Chip Hardware Accelerators for Biological Sequence Alignment
—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Souradip Sarkar, Gaurav Ramesh Kulkarni, Partha Pr...
FOCS
2010
IEEE
15 years 4 months ago
Stability Yields a PTAS for k-Median and k-Means Clustering
We consider k-median clustering in finite metric spaces and k-means clustering in Euclidean spaces, in the setting where k is part of the input (not a constant). For the k-means pr...
Pranjal Awasthi, Avrim Blum, Or Sheffet